| Datum | Tijd | Thuis | Uit |
|---|
| 29-01-2022 | 17:00 | Landslake Lions V18 1 | BS Leiden V18 1 |
| 05-02-2022 | 17:00 | Attacus V18 1 | Landslake Lions V18 1 |
| 12-02-2022 | 17:00 | Landslake Lions V18 1 | Uitsmijters V18 1 |
| 20-02-2022 | 17:30 | Lokomotief V18 1 | Landslake Lions V18 1 |
| 26-02-2022 | 17:00 | Landslake Lions V18 1 | Dozy BV Den Helder V18 1 |
| 06-03-2022 | 14:30 | BC Utrecht Cangeroes V18 1 | Landslake Lions V18 1 |
| 12-03-2022 | 17:00 | Landslake Lions V18 1 | BC APOLLO Amsterdam V18 1 |
| 20-03-2022 | 14:00 | H.S.V. Basketball V18 1 | Landslake Lions V18 1 |
| 26-03-2022 | 17:00 | Landslake Lions V18 1 | CBV Binnenland V18 1 |
| 03-04-2022 | 16:00 | BC Triple Threat V18 1 | Landslake Lions V18 1 |
| 09-04-2022 | 15:00 | BV Hoofddorp V18 1 | Landslake Lions V18 1 |
| 16-04-2022 | 11:00 | BC APOLLO Amsterdam V18 1 | Landslake Lions V18 1 |
| 01-05-2022 | 11:00 | Landslake Lions V18 1 | Basketbal Academie Limburg V18 1 |
| 07-05-2022 | 13:00 | Sportiff Company Grasshoppers V18 1 | Landslake Lions V18 1 |
| 14-05-2022 | 13:30 | CBV Binnenland V18 1 | Landslake Lions V18 1 |
| 21-05-2022 | 17:00 | Landslake Lions V18 1 | BC Triple Threat V18 1 |
| 28-05-2022 | 17:00 | Landslake Lions V18 1 | BV Hoofddorp V18 1 |
| 30-06-2022 | 08:30 | Uitsmijters V18 1 | Landslake Lions V18 1 |
